@article{Pérez Meza_Jaramillo Núñez_Cuevas Otahola_Arriaga Hernández_Sánchez Rinza_2021, title={Determination of early bone metastasis on Bone Scans Using the Gray Levels Histogram}, volume={42}, url={https://rmib.com.mx/index.php/rmib/article/view/1119}, DOI={10.17488/RMIB.42.2.1}, abstractNote={<p>The aim of this paper is to show a technique to speed up the interpretation of bone scans in order to determine the presence of early bone metastasis. This is done using the gray levels histogram of the region of interest. The technique is intended to assist in the bone scans interpretation in order to provide a successful diagnosis. During the analysis, three types of histograms were observed on the regions of interest. If the histogram is narrow and shifted toward the origin, the bone scan is free of metastasis.  If it is shifted to the right and slightly broadened, indicates the presence of a bone anomaly different from a metastasis. On the other hand, if the histogram is more broadened and shifted to the right, is suggests the presence of metastasis. This histogram is characterized by displaying small curls on the right side providing information about the metastatic disease stage, which could be low-amplitude peaks and have a short length, if the metastasis is in early stage, or high-amplitude peaks and a long length, if is advanced.  Finally, the analyzed region is displayed in false color considering the minimum gray levels observed in the histogram.</p>}, number={2}, journal={Revista Mexicana de Ingenieria Biomedica}, author={Pérez Meza, Mónica and Jaramillo Núñez, Alberto and Cuevas Otahola, Bolivia and Arriaga Hernández, Jesús Alonso and Sánchez Rinza, Bárbara Emma}, year={2021}, month={Feb.}, pages={6–14} }