Evaluación biomecánica de un modelo de defecto óseo en tibia de rata
Abstract
The study of bone defects repair is one important aspect in orthopedic and odontological surgery. Missing segments of bone from trauma, tumors, and infection can be considered of critical size (do not repair spontaneously) and of non-critical size (do repair spontaneously). The goal of this work was to assess a non-critical bone defect model, through the biomechanical analysis of the three point flexural test in the rat tibia. We studied three groups: intact (control), defect and defect left to repair spontaneously for 21 days. We found a significant difference between the control group and the bone defect group, which validates the model; furthermore, the energy at maximum load was significantly different between the control group and the spontaneous repair group, an observation that indicates that healing of the bone defect is indeed the healing process of a bone defect can be evaluated; in addition, the low cost of our model allows the study of new materials, substances and methods aimed to accelerate bone repair.
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